The term “clinical trial” is used for all studies investigating the efficacy and/or safety of drugs or other treatment modalities. This handbook is intended as an aid for “investigators” (physicians and dentists) and other persons participating in clinical trials. The number of clinical trials is steadily increasing and all medical disciplines are represented. The author begins with a description of the starting points as seen through the eyes of health care providers, pharmaceutical companies and society. Afterwards, she reviews the different phases of a clinical trial from planning to reporting. The book concludes with appendices covering such things as ethical regulations, protocol templates and a glossary of common terms. Second edition